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Disadvantages of gene therapy

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What is the biggest downfall of gene therapy? Delivering a gene to the wrong tissue would be inefficient, and it could cause health problems for the patient. For example, improper targeting could incorporate the therapeutic gene into a patient's germline, or reproductive cells, which ultimately produce sperm and eggs.
Why are people against gene therapy? Arguments Against Gene Therapy Three arguments sometimes raised against gene therapy are that it is technically too dangerous, that it discriminates or invites discrimination against persons with disabilities, and that it may be becoming increasingly irrelevant in some cases.
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Gene therapy
Risks · Unwanted immune system reaction. Your body's immune system may see the newly introduced viruses as intruders. · Targeting the wrong cells.
https://www.mayoclinic.org/tests-procedures/gene-therapy/about/pac-20384619
Gene Therapy Definition, Pros & Cons
Gene therapy is an innovative approach to medicine that uses genetic material to prevent, treat and potentially even cure disease. In gene therapy, genetic ...
https://my.clevelandclinic.org/health/treatments/17984-gene-therapy
What Are the Pros and Cons of Gene Therapy?
As with any medication, toxicity and side effects can still occur. The use of gene therapy is relatively new, so there may be unpredictable ...
https://www.goodrx.com/health-topic/gene-therapy/gene-therapy-pros-cons
Challenges In Gene Therapy
It is very hard to introduce new genes into cells of the body and keep them working. And there are financial concerns: Can a company profit from developing a ...
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https://learn.genetics.utah.edu/content/genetherapy/challenges/
Is gene therapy safe?
The earliest studies showed that gene therapy could have very serious health risks, such as toxicity, inflammation, and cancer.
https://medlineplus.gov/genetics/understanding/therapy/safety/
Successes and challenges in clinical gene therapy - PMC
The conditioning imposes risks of organ toxicity, infections, pancytopenia requiring transfusions and often antibiotics, as well as discomforts ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678346/
Gene Therapy and Genetic Engineering
Three arguments sometimes raised against gene therapy are that it is technically too dangerous, that it discriminates or invites discrimination against persons ...
https://medicine.missouri.edu/centers-institutes-labs/health-ethics/faq/gene-therapy
What Is Gene Therapy: Risks, Benefits, and More
Risks of Gene Therapy · Unwanted Immune System Reaction · Wrong Target Cell · Infection Caused by Viral Vector · Possible Tumor.
https://www.verywellhealth.com/gene-therapy-5214362
What are the ethical issues surrounding gene therapy?
Because gene therapy involves making changes to the body's basic building blocks (DNA), it raises many unique ethical concerns.
https://medlineplus.gov/genetics/understanding/therapy/ethics/
Pros and cons of gene therapy
Gene therapy adds a new gene where the current one is missing or mutated, edits a gene to produce more advantageous functions, or silences a gene to reduce the ...
https://www.singlecare.com/blog/gene-therapy-benefits/
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