Most recent job postings at New Scientist
via BeBee posted_at: 2 days agoschedule_type: Full-time
The Position The Department of Translational Oncology in Genentech Research has an opportunity for a highly motivated Scientist 2/Scientist 3 to join in our mission of developing meaningful therapies for the treatment of cancer. The successful candidate should have demonstrated hands-on skills in using mouse tumor models of cancer to understand the tumorigenic process and to identify and/or... assess therapeutic targets. This role is an opportunity The Position
The Department of Translational Oncology in Genentech Research has an opportunity for a highly motivated Scientist 2/Scientist 3 to join in our mission of developing meaningful therapies for the treatment of cancer. The successful candidate should have demonstrated hands-on skills in using mouse tumor models of cancer to understand the tumorigenic process and to identify and/or... assess therapeutic targets. This role is an opportunity to join cutting-edge research-based project teams doing high quality oncology drug development to advance molecules to clinical testing. The successful candidate would provide superb technical support in generating the key in vivo efficacy and pharmacodynamic data essential to drive projects into clinical development.

Who You Are:

Qualified candidates will possess the following skills and experience with the level of the position commensurate with the candidates experience:
• Bachelors, Masters, or Ph.D. degree in animal science, veterinary medicine, cell biology, immunology, oncology or related science
• 3+ years hands-on relevant experience with murine models; at least 8 years of experience is required for the Scientist 3 level
• Demonstrated expertise in the design, execution and analysis of in vivo tumor models
• Proficiency in IP, IV, SC, and PO dosing, and blood and tissue collection
• Ability to process tumor tissue for pharmacodynamic studies, including generation of cell suspensions, RNA, DNA, and protein
• Excellent communication skills, ability to work as part of a team, and to present experimental results in a team setting
• Experience with oncology or immunology projects preferred
• Proven ability to independently design, execute, and interpret experiments
• Excellent attention to detail and ability to maintain careful study notes using an online database system and electronic notebooks
• Highly qualified candidates will have familiarity and/or experience with modern biological techniques and assays, including cell culture, western blotting, ELISA, RT-PCR, flow cytometry, and CRISPR-Cas9-based cell editing
• Track record of success as evidenced by publication record and/or evidence of sustained contributions in a biotechnology or pharmaceutical setting

Relocation benefits are not available for this job posting.

#researcherjob

Who we are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated againstCOVID-19 in accordance with customer requirements, the companys health and safety obligations and/or applicable law or guidelines.

Diversity and Inclusion (D&I)are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. Were focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.For more information about equal employment opportunity, visit ourGenentech Careers Homepage
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via Mendeley posted_at: 2 days agoschedule_type: Full-time
The Position Who you are ... Your main responsibilities • Performs daily, monthly and quarterly instrument and equipment maintenance and cleaning tasks. • Troubleshoots minor equipment malfunctions by performing operational tests. • Monitors and maintains usage logs for all equipment and instruments. Monitors, schedules and delivers portable instruments for calibration and maintains necessary documentation. • Monitors and completes routine The Position
Who you are
...
Your main responsibilities
• Performs daily, monthly and quarterly instrument and equipment maintenance and cleaning tasks.
• Troubleshoots minor equipment malfunctions by performing operational tests.
• Monitors and maintains usage logs for all equipment and instruments. Monitors, schedules and delivers portable instruments for calibration and maintains necessary documentation.
• Monitors and completes routine maintenance on Thermal equipment (refrigerators, freezers, incubators, etc.).
• Coordinates equipment preventative maintenance, repairs and validations with third party vendors.
• Prepares and schedules incoming and outgoing stained slide and/or reagent shipments.
• Perform scheduled lab inspections. May assist with preparation or lab inspections roster and ensure inspections completed as scheduled.
• Serves as primary trainer for new Lab Tech/Assistants in the area.
• May perform staining runs for new BenchMark instrument installations.
• Other duties as assigned by management.

Your key qualifications
• H.S. Diploma is required. Some college coursework in a relevant field is preferred
• 5 years of relevant lab experience is required
• Experience operating Ventana instruments. Experience with monthly and quarterly maintenance

Your Knowledge, Skills and Abilities
• Some laboratory and knowledge of general laboratory practices
• Skill in inventory management
• Ability to use hand tools such as screwdrivers, wrenches, nut-drivers and various other hand tools
• Ability to use test equipment such as flow meters, pH meters, precision weight scales, and pressure meters
• Excellent communication and interpersonal skills. Organizational and self motivation is highly desirable
• Attention to detail in written instructions and documentation
• Ability to lift up to 45 pounds

Relocation benefits are not available for this job posting.

Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, weve become one of the worlds leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Ventana Medical Systems, Inc. (Ventana), a member of the Roche Group, innovates and manufactures instruments and reagents that automate tissue processing and slide staining for cancer diagnostics. Our integrated staining, workflow management and digital pathology solutions optimize laboratory efficiency to reduce errors and support diagnosis for pathology professionals. Together with Roche, Ventana is driving personalized healthcare through accelerated drug discovery and companion diagnostics.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated againstCOVID-19 in accordance with customer requirements, the companys health and safety obligations and/or applicable law or guidelines.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individuals race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in connection with the on-line application process, please email us atUS.Accommodation@roche.com
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via Mendeley posted_at: 24 days agoschedule_type: Full-time
The Position The Scientist position (GenMark, Carlsbad, CA) is responsible for planning, executing and analyzing innovative scientific experiments leading to development and integration of new molecular diagnostic assays and manufacturing process improvements for molecular diagnostic products. Specifically, this individual works cross-functionally to investigate, ideate solutions, and implement... product and process improvements. The individual also The Position
The Scientist position (GenMark, Carlsbad, CA) is responsible for planning, executing and analyzing innovative scientific experiments leading to development and integration of new molecular diagnostic assays and manufacturing process improvements for molecular diagnostic products. Specifically, this individual works cross-functionally to investigate, ideate solutions, and implement... product and process improvements. The individual also provides stability testing for new products and surveillance testing for on market products.

Duties and Responsibilities:
• Investigate modifying existing chemistries and alternative chemistries to improve detection technology into current and future microfluidic platforms
• Initiates, directs and executes innovative scientific research and/or development strategies; can act as technical lead for a development project
• Identifies and solves problems in experimental designs.
• Investigates, creates, and develops new methods and technologies for project advancement.
• Independently plans and designs experiments; critically analyzes complex data.
• Able to independently drive results, and is collaborative within and between teams to achieve departmental goals
• Open minded and pragmatic in planning experiments and interpreting data, seeking to achieve the most information with the least burdensome approach
• Maintains high level of expertise through scientific literature and competitor products.
• Exercises judgment within broadly defined practices and policies.
• May supervise junior associates in daily experiments & troubleshooting.
• May contribute toward or produce invention disclosures, patents and publication.
• Assignments are broad in nature, usually requiring significant originality and ingenuity

Education and Experience:
• BS/MS or Ph.D. in Organic chemistry, Biochemistry, Molecular Biology, Analytical Chemistry or a related field
• Based on level of degree achieved - BS ten (10+) years of experience; MS five (5+) or PhD one or more (1+) years of experience as a scientist in medical diagnostic product development, customer or manufacturing technical support

Skills Technical & General :
• Experience or familiarity with molecular biology techniques is essential
• Experience or familiarity with bioinformatics and PCR is essential
• Experience with method development and performing analytical tests
• Established technical expertise; serves as a resource to other groups.
• Possesses and applies comprehensive knowledge of a particular field of specialization to the completion of complex assignments.
• Demonstrates competence in data analysis, research design and the evaluation of new techniques and procedures for products, systems or technologies.
• Excellent organizational skills, including the ability to efficiently evaluate, prioritize and handle multiple changing projects and priorities.
• Proven ability to lead and provide work direction to junior associates.

The expected salary range for this position based on the primary location of California is $73,200 - $103,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are not available for this job posting

Who we are
GenMark is now a proud member of the Roche Group, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. As a global leader in healthcare, Roche Diagnostics offers a broad portfolio of products, tools and services that help in the prevention, diagnosis and management of diseases like HPV, HIV, hepatitis and diabetes as well as other medical conditions, such as fertility and blood coagulation. With the addition of GenMark to the Roche Group, syndromic infectious disease diagnostics is now added to the long list of disease states and conditions that the Roche Group addresses. GenMarks ePlex true sample-to-answer system offers unique solutions to address the most significant challenges facing clinical laboratories, while supporting hospital systems to deliver patient-centered, value-based care. ePlex streamlines the diagnostic workflow from physician order entry to the final test report and is the true sample-to-answer solution designed to improve patient care, reduce costs, and increase lab efficiency. GenMark is headquartered in Carlsbad, California.

GenMark is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individuals race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law
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via Mendeley posted_at: 2 days agoschedule_type: Full-time
Data Analyst - Signal Processing Permanent Position... £35,000 - £50,000 (commensurate with experience) + Excellent Benefits Based in London Do you have experience in raw signal processing, data analysis, and data visualisation? Would you like to work for a ground-breaking medical diagnostics company in London? My client is a well-funded and commercially successful medical diagnostics company, with a diverse and innovative product development Data Analyst - Signal Processing

Permanent Position...

£35,000 - £50,000 (commensurate with experience) + Excellent Benefits

Based in London

Do you have experience in raw signal processing, data analysis, and data visualisation?

Would you like to work for a ground-breaking medical diagnostics company in London?

My client is a well-funded and commercially successful medical diagnostics company, with a diverse and innovative product development pipeline. Due to ongoing success and growth, they are looking to hire a Data Analyst - Signal Processing to be responsible for the ongoing analysis of data sets generated by research and development programmes, supporting product conception, research & development, optimisation and commercialisation.

Key Responsibilities of the Data Analyst - Signal Processing will include;
• Analysis of data sets generated by ongoing medical and clinical diagnostics R&D, including but not limited to processing of raw electronic signals generated by Next Generation Sequencing (NGS), qPCR and Microarrays.
• Development of novel analysis methodologies, using external, internal and self-written software, typically to support laboratory activities.
• Communicate with scientists, engineers, bioinformaticians, software engineers and other colleagues within the organisation to maintain alignment of activities, including presentation of data at group meetings.
• Effective management of required documentation in accordance with company quality management system and ISO 13485 standards.

To be considered for the Data Analyst - Signal Processing vacancy, you'll need the following skills and experience;
• BSc / MSc in a relevant discipline (e.g. Biomedical Engineering, Applied Mathematics, Chemistry, Physics, Biochemistry, Bioinformatics, Computer Science etc.) or equivalent working experience.
• Proficient in Python, with hands-on coding and script-writing experience, including the analysis and summation of experimental data.
• Experience in raw signal processing, data analysis, and data visualisation.
• Good mathematical ability, with a methodical and logical approach.
• Innovative problem-solving abilities, self-motivated and goal-oriented to achieve project goals within specified timelines.
• Responds positively to intellectual and time challenges.
• Excellent organisational and communication skills, able to engage in multidisciplinary discussions with teams across programs to transfer and apply knowledge.

Key Words: "Data Analyst, Data Analysis, Data Scientist, Signal Processing, Python, Coding, R, Script, Script Writing, Medical Diagnostics, Molecular Diagnostics, Diagnostics, IVD, London"

Please apply online or contact Katie-May Kress at CY Partners for more information
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via Mendeley posted_at: 16 days agoschedule_type: Full-time
The Position Healthcares future is data driven. As an Analytical Data Scientist at Roche Pharma, youll be actively shaping this future as a member of Data and Statistical Sciences within Product Development Data Sciences. Analytical Data Scientists at Roche are essential leaders in the field; they drive and implement a broad range of quantitative drug development strategies; they bring data to... life and enable the organization to make the best possible The Position
Healthcares future is data driven. As an Analytical Data Scientist at Roche Pharma, youll be actively shaping this future as a member of Data and Statistical Sciences within Product Development Data Sciences. Analytical Data Scientists at Roche are essential leaders in the field; they drive and implement a broad range of quantitative drug development strategies; they bring data to... life and enable the organization to make the best possible data-driven decisions.

Responsibilities

As an Analytical Data Scientist, you are responsible for delivery of products (data tabulation, analysis datasets, statistical tables/listings/figures, interactive applications, etc.) that reflect clinical trial data and analysis. You will support study reporting by producing these deliverables yourself, and/or in collaboration with internal and external colleagues. You will provide analytical and programming expertise, and will contribute to production of packages and functions that can be used across studies and molecule programs. You will also support regulatory submissions to health authorities, and will contribute to data standardization in order to maximize reusability.

As an Analytical Data Scientist, you may also provide study or cross-study leadership at the molecule or franchise level (depending on experience and demonstrated leadership skills). In leadership roles, you will provide strategic advising, influence decision-making, and foster strong collaborations with cross-functional stakeholders.

Technical Qualifications:
• Expertise in manipulating and analyzing various data types related to clinical trials, such as patient characteristics, lab values, and imaging (might also include digital health, genomic data, and biomarkers).
• Good understanding of clinical data and knowledge of CDISC data standards.
• Experience in transforming, organizing and analyzing healthcare data.
• Expertise in using programming languages (R preferred) to derive variables and produce statistics.
• Expertise in writing reusable functions and packages.
• Knowledge of modern version control systems and software development techniques.
• Understanding of open source software development.

General Qualifications:
• College/University degree bachelor degree or higher or equivalent education in scientific, medical or relevant technical discipline.
• Experience in the pharmaceutical/biotech industry is preferred.
• Understanding of the end-to-end drug development lifecycle.
• Track record of establishing successful internal partnerships and collaborations.
• Knowledge of agile behaviors and methodologies.
• Excellent communication skills. Fluency in written and spoken English Influential and confident communicator.
• Ability to work across multiple cultures and countries.
• Knowledge of GCP, international regulations, guidelines and their application, and all other applicable compliance standards is a plus.
• Willingness to travel as required.

Education Level: Bachelor, Masters degree or PhD (Masters or higher preferred)

Preferred Major(s): Biostatistics, applied statistics, data science.

The expected salary range for this position based on the primary location of South San Francisco, California is between $110k and $204k of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Who we are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated againstCOVID-19 in accordance with customer requirements, the companys health and safety obligations and/or applicable law or guidelines.

Diversity and Inclusion (D&I)are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. Were focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.For more information about equal employment opportunity, visit ourGenentech Careers Homepage
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via Mendeley posted_at: 2 days agoschedule_type: Full-time
The Position Provide leadership and technical support to manufacturing personnel to produce high quality products for our customers. Responsibilities include direct management of production assemblers, fulfillment of the production schedule, and ensuring quality compliance. Provide operations expertise, and technical skills to the supervision and support of manufacturing personnel to achieve New... Product Development, Continuous Improvement, Quality, The Position
Provide leadership and technical support to manufacturing personnel to produce high quality products for our customers. Responsibilities include direct management of production assemblers, fulfillment of the production schedule, and ensuring quality compliance. Provide operations expertise, and technical skills to the supervision and support of manufacturing personnel to achieve New... Product Development, Continuous Improvement, Quality, Compliance and Operational metrics.

POSITION REQUIREMENTS
• Supervise production personnel and activities to effectively support manufacturing needs to meet customer requirements for existing commercial products, new product introductions and R&D builds.
• Hire, train, develop and evaluate production personnel to ensure the appropriate resources and talent are in place.
• Plan and schedule resources and activities to ensure business needs are satisfied.
• Tracks, analyzes, summarizes and reports key indicator data and metrics for areas of responsibility.
• Evaluate direct reports performance on an annual basis in a written performance review.
• Responsible for ensuring compliance to quality systems (FDA, GMP, QSR, ISO), product specifications, process instructions, safety requirements and company policies.Includes the diligent management of non-conformances to ensure appropriate corrective and preventive actions.
• Proactively identifies potential failure modes relative to quality or business risks.
• Collaborate and provide manufacturing input and support to New Product teams, including the design for manufacturing (DFM) guidance, input on process / tooling development and developing/refining manufacturing instructions.
• Collaborate with Supply Chain, Logistics, Manufacturing Engineering and Quality to drive value stream and lean manufacturing improvement initiatives.
• Provide technical guidance and input regarding new processing strategies and associated equipment procurement.
• Identify and implement lean manufacturing opportunities in effort to improve quality, increase productivity, reduce costs and reduce cycle times.
• Develop and sustain the manufacturing team as a quality minded culture driven by focusing on customer service (external and internal), outstanding compliance, continuous improvement activities that support business objectives.

Preferred Education and Experience
• B.S. degree in Engineering or Science, or AA degree plus 3 years supervisory experience in medical device, pharmaceutical or similarly regulated environment, or High School Diploma plus 5 years supervisory experience in medical device, pharmaceutical or similarly regulated environment
• Minimum of 6 years of related experience in the medical device, pharmaceutical or similarly regulated industry.

Skills Technical
• 2-4 years experience in Technical Supervision and/or Engineering in the medical device or pharmaceutical industry.
• Working knowledge of quality system requirements (QSR) and good manufacturing practices (GMP).
• Experience working with a clean room environment, and application of environmental procedures.
• Experience working with manufacturing/MRP systems (QAD preferred)
• Experience and/or certification in LEAN Manufacturing principles.
• Experience and prior training (or ideally certification) with Lean Manufacturing and/or Six Sigma methodologies. Experience with Statistical Process Control a plus.

Skills General
• Must be a hands-on, self-directed, organized and conscientious individual
• Complete work in a timely, accurate and thorough manner
• Must be able to think and work both tactically and strategically to provide financial and operational needs to GenMarks business
• Effective analytical problem solving and decision-making skill
• Strong time management and organizational skills in a dynamic, constantly changing environment
• Strong communication skills including the ability to communicate with all levels within the organization
• Ability to read, write and analyze complex documents
• Ability to respond effectively to sensitive inquiries, customer inquiries or complaints as well as communicate effectively both orally and in writing with management, peers and individuals
• Ability to work effectively, exhibit a professional manner and establish constructive working relationships
• Strong problem-solving, judgment and decision-making skills are required

SUPERVISORY RESPONSIBILITIES (if applicable)
• 20-50 Manufacturing Technicians and other hourly personnel

WORK ENVIRONMENT

The essential functions of the job are usually performed in an environmentally controlled facility where the noise level in the work environment is usually moderate. This position may involve a combination of office and biotechnology laboratory environments. The employee may be exposed to hazardous chemicals, blood borne pathogens and automated equipment.

While performing the job duties, the employee is regularly required to sit; reach with hands and arms and talk or hear. The employee is frequently required to stand and walk. The employee may sometimes be required to lift and/or move up to 35 pounds. Specific vision abilities required by this job include close vision, distance vision, color vision and ability to adjust focus.
• Relocation assistance is NOT available for this role*

The expected salary range for this position based on the primary location of California is $59,000.00 to $109,600.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Who we are
GenMark is now a proud member of the Roche Group, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. As a global leader in healthcare, Roche Diagnostics offers a broad portfolio of products, tools and services that help in the prevention, diagnosis and management of diseases like HPV, HIV, hepatitis and diabetes as well as other medical conditions, such as fertility and blood coagulation. With the addition of GenMark to the Roche Group, syndromic infectious disease diagnostics is now added to the long list of disease states and conditions that the Roche Group addresses. GenMarks ePlex true sample-to-answer system offers unique solutions to address the most significant challenges facing clinical laboratories, while supporting hospital systems to deliver patient-centered, value-based care. ePlex streamlines the diagnostic workflow from physician order entry to the final test report and is the true sample-to-answer solution designed to improve patient care, reduce costs, and increase lab efficiency. GenMark is headquartered in Carlsbad, California.

GenMark is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individuals race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law
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via Mendeley posted_at: 15 days agoschedule_type: Full-time
The Position Summary - Scientist 3, Single Cell Genomics ... The Department of Cell and Tissue Genomics is seeking a creative, detail-oriented, and motivated Scientist 3 to develop and apply cutting-edge single cell genomic techniques to study cancer biology. The successful candidate will lead development and establishment of new techniques while collaborating with colleagues in the departments of Molecular Oncology, Discovery Oncology, Cancer Immunology, The Position
Summary - Scientist 3, Single Cell Genomics
...
The Department of Cell and Tissue Genomics is seeking a creative, detail-oriented, and motivated Scientist 3 to develop and apply cutting-edge single cell genomic techniques to study cancer biology. The successful candidate will lead development and establishment of new techniques while collaborating with colleagues in the departments of Molecular Oncology, Discovery Oncology, Cancer Immunology, and/or Bioinformatics to interrogate the molecular mechanisms underlying disease states and identify candidate targets for therapeutic intervention. This is a hands-on position with both experimental and computational analysis components.

Responsibilities
• Develop and apply multimodal single cell technologies in cell lines, disease models, and primary tissue samples
• Analyze and interpret single cell genomics data in collaboration with bioinformaticians
• Design, optimize, and execute experiments to investigate mechanisms of disease progression and response to therapy
• Communicate results through scientific publications and presentations
• Contribute to lab organization and culture and help identify new research opportunities

Qualifications
• Doctorate degree in a relevant field, including molecular biology, cancer biology, genetics, immunology, systems biology, developmental biology, biochemistry, and/or biomedical engineering. Postdoctoral or equivalent training is a plus.
• Strong background in NGS assays, including epigenetic assays. Single cell genomic assay experience preferred.
• Experience with genomic data analyses and interpretation (R and/or Python)
• Experience with protein detection methods is preferred (eg. flow cytometry/FACS, Western blotting, IF)
• Experience with technology development and optimization is preferred
• Experience with CRISPR genome editing and high throughput screens is a plus
• Experience with tissue processing for single cell genomic assays is a plus
• Productive publication record in high quality scientific journals

The expected salary range for this position based on the primary location of South San Francisco, CA is 98,200 to 182,400. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation is offered for this position.

#researcherjob

#LI-TH2

Who we are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated againstCOVID-19 in accordance with customer requirements, the companys health and safety obligations and/or applicable law or guidelines.

Diversity and Inclusion (D&I)are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. Were focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.For more information about equal employment opportunity, visit ourGenentech Careers Homepage
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via Mendeley posted_at: 1 day agoschedule_type: Full-time
The PositionPosition Summary Doing now what patients need next. We are looking for a Principal Software Engineer to help develop and lead the next generation of products for our Imaging Scientists in Digital Pathology. We are part of the Computational Sciences & Informatics Organization at Roche and our scientists need platforms for the visualization and digital interactions with slide imagery... training of Machine Learning models, and Inferencing The PositionPosition Summary
Doing now what patients need next. We are looking for a Principal Software Engineer to help develop and lead the next generation of products for our Imaging Scientists in Digital Pathology. We are part of the Computational Sciences & Informatics Organization at Roche and our scientists need platforms for the visualization and digital interactions with slide imagery... training of Machine Learning models, and Inferencing of tissue slide imagery. These are important R&D and humanity efforts that will help change lives!

Key Qualifications
• 6+ years of experience as a Software Engineer architecting and building scalable backend systems and APIs, with particular attention to performance and security with the ability to work in the frontend as well. Or the converse qualifies as well, extensive experience in frontend technologies and development, with the ability to also work and contribute in the backend as well.
• Experience using Git, familiarity with CI/CD (GitLab Preferred), and Unix/Linux based systems required
• Experience in different programming languages such as Python/Java/Typescript required
• Experience in front end frameworks like either ReactJS and/or AngularJS required
• Experience in Unit Testing required
• Experience in mentoring engineers is required. The role goes beyond only moving tasks across the JIRA board.
• Experience in gathering requirements and translating them into realistic and measurable technical requirements and solutions. This is required.
• Experience in working with cross-functional teams, product, operations, and IT
• Excellent communication and organizational skills
• The successful candidate is someone who comes with an open mind to working with different technologies and enjoys learning new skills and technologies
• Experience in containerization technologies, kubernetes preferred but not required
• Experience developing solutions in the public cloud (Azure, GCP, AWS), AWS preferred but not required
• A plus if you have experience in WebGL, ThreeJS, PixiJS, or others.
• A plus if you have experience in code security and healthcare compliance, not required
• A plus if you have Drupal and PHP experience, not required
• A plus if you have experience in Machine Learning / Deep Learning systems, building data pipelines, MatLab, Medical Imaging Systems and digital imaging formats, not required
• Santa Clara, CA is the preferred location; however, remote in the US is available for the right candidate

Description

As a Principal Software Engineer here you will help build the next generation of Imaging Platforms. This team is responsible for helping with the transition from our legacy system to our newer platforms, and as a Principal Software Engineer, your role is multidisciplinary. You would be responsible to write clean and elegant code, work in different technologies, mentor engineers on best practices, perform code reviews, recommend new technologies and solutions, solve problems, and more. In this role, you will:
• Write code to create new features, like overlaying inferencing data over a slide image on the browser, or creating backend workflow systems to spin up analysis containers
• Work with our Imaging Scientists to help with the workflow requirements of their algorithms, answering the question of how can they interface with our systems?
• Evolve our existing imaging platforms from a feature and design perspectives
• Be very active in the code-review process and mentor engineers
• Put to work your experience in best practices and favor them over re-inventing solutions
• Find simple solutions to complex business and technical problems
• Work closely with our Senior Principal Software Engineer and help with architecture as needed
• Jump in when issues to our production systems arise
• Document everything

Education
• Bachelors Degree in Computer Science, Engineering, or Related Field. Masters Degree preferred.

The expected salary range for this position based on the primary location of Santa Clara, CA is $129,700-$240,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.Benefits

Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, weve become one of the worlds leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated againstCOVID-19 in accordance with customer requirements, the companys health and safety obligations and/or applicable law or guidelines.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individuals race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in connection with the on-line application process, please email us atUS.Accommodation@roche.com
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via Mendeley posted_at: 2 days agoschedule_type: Full-time
The Position We seek a talented and motivated Scientist to join Genentechs Oncology Reverse Translation (RT) team in South San Francisco. Our team aims to develop next generation therapeutic strategies and targets by mining our clinical datasets for new insights into how malignancies respond or resist existing treatments, and then validating those findings in preclinical models. In this role, you... will join a small RT in vivo pharmacology team that The Position
We seek a talented and motivated Scientist to join Genentechs Oncology Reverse Translation (RT) team in South San Francisco. Our team aims to develop next generation therapeutic strategies and targets by mining our clinical datasets for new insights into how malignancies respond or resist existing treatments, and then validating those findings in preclinical models. In this role, you... will join a small RT in vivo pharmacology team that leads and conduct in vivo experiments in support of high priority RT projects. You will closely collaborate with the cross-functional RT team as well as other groups in Translational Oncology, Research, and Translational Medicine.

Responsibilities:
• Plan, conduct, and analyze mouse model experiments to test and validate key mechanistic hypotheses and therapeutic targets identified by the RT team.
• Develop novel mouse models to support your projects.
• Support additional project work such as cell culture, flow cytometry, and in vitro mechanistic assays.
• Present to and participate at team, department, and other meetings to support project development and decision making.
• Publish your work in high quality journals.

Who you are:
• Bachelors or Masters degree in cell biology, immunology, oncology, or a related field.
• Demonstrated expertise and at least 3 years (Scientist 2) or 6 years (Scientist 3) of hands-on experience with mouse models of cancer.
• Proficiency in IP, IV, SC, and PO dosing as well as blood and tissue collection.
• Training in immunology and ex vivo techniques such as cell isolation and culture, cellular immunology assays, and flow cytometry is advantageous.
• Stellar communication and time management skills. Ability to work collaboratively.
• Track record of success as evidenced by publications and/or sustained contributions in a biotechnology or pharmaceutical setting.

What to expect from us:
• A collaborative, multidisciplinary organization dedicated to rigorous science and improving patient health.
• Access to state-of-the-art technologies and pioneering research.
• Campus-like lifestyle with a healthy work-life balance.
• Extensive mentorship and career development opportunities.

The expected salary range for this position based on the primary location of California is $82,800 - $185,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#LI-SKILLIAN
#devsci
#OBDCIT

Who we are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated againstCOVID-19 in accordance with customer requirements, the companys health and safety obligations and/or applicable law or guidelines.

Diversity and Inclusion (D&I)are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. Were focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.For more information about equal employment opportunity, visit ourGenentech Careers Homepage
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via Mendeley posted_at: 9 days agoschedule_type: Full-time
The Position As a part of the Data Analytics team at GenMark Dx, you will play a key role in bringing data analytics expertise to cross disciplinary project teams for experimental design and interpretation, customer support, root cause investigation, process improvement, and manufacturing digitalization. You have an analytical mindset and a deep understanding of molecular diagnostics, ranging... from assay development to manufacturing scale-up, especially The Position
As a part of the Data Analytics team at GenMark Dx, you will play a key role in bringing data analytics expertise to cross disciplinary project teams for experimental design and interpretation, customer support, root cause investigation, process improvement, and manufacturing digitalization. You have an analytical mindset and a deep understanding of molecular diagnostics, ranging... from assay development to manufacturing scale-up, especially as related to GenMarks unique technologies. You will apply your data analysis skill set to solving complex problems by combining product performance data, from quality control and from the field, with manufacturing production data. You are motivated by a boundless curiosity and will take the initiative to gain increasing mastery of data science tools and programming languages. You will work collaboratively within the Data Analytics team to quickly prototype, validate, and deploy analytical solutions and implement data automation. You have a knack for clearly communicating across technical boundaries and distilling complicated information for key stakeholders.

POSITION REQUIREMENTS
• Able to independently drive results and collaborate with teams to achieve departmental goals
• Takes initiative and demonstrates enthusiasm for advancing our analytics strategy
• Manipulates and analyzes heterogeneous and complex data sets to provide deeper insights into product performance and manufacturing processes
• Designs, enhances, and implements data collection methods to assemble the necessary data to achieve project aims
• Collaborates with various stakeholders to define methods for data collection, analysis and reporting
• Independently develops methods for the utilization of manufacturing data to improve key performance metrics such as accuracy, reliability and yield
• Investigates, creates, and develops new methods and technologies for project advancement
• Works collaboratively with scientists and engineers to plan and design experiments with special attention to the analysis and interpretation of the experimental data using statistical methods
• Maintains high level of expertise through continued technical training in programming and data science
• Acts as a technical lead as necessary to provide leadership towards the application of scientific and data best practices
• Exercises judgment within broadly defined practices and policies
• Assignments are broad in nature, usually requiring significant originality and ingenuity
• Utilizes comprehensive understanding of GenMark's data structures and metrics as they relate to product development, manufacturing, and customer experience
• May contribute toward or produce invention disclosures, patents and publication
• Communicates results clearly and effectively through visual displays of quantitative information

Education and Experience
• BS/MS or PhD in a science, engineering or related field of study
• Based on level of education, the preferred experience in relevant professional roles is BS 10+ years, MS 8+ years, PhD 4+ years

Skills Technical
• Good understanding of applied statistics (distributions, regression) and ability to use statistics to design experiments and interpret data
• Experience analyzing and manipulating large datasets, experience with query languages such as SQL is a plus
• Familiarity with a BI platform (Spotfire, Tableau, Power BI)
• Demonstrated success with scripting language (JMP scripting language, python, or R)
• Good documentation for recording experiments and scripting, experience with version control is a plus
• Experience with the development and manufacturing of molecular diagnostics from product concept through FDA clearance
• Familiarity with clinical molecular and microbiology lab workflows and techniques
• Understanding of and hands-on experience with molecular biology laboratory techniques

Skills General
• Must be a hands-on, self-directed, organized and conscientious individual
• Complete work in a timely, accurate and thorough manner
• Strong understanding of scientific principles and concepts
• Knowledge of molecular techniques (nucleic acid extraction, reverse transcription, PCR, immunoassays, DNA quantification)
• Motivated to create solutions to problems in healthcare with the goal of improving patient outcomes and clinician experiences
• Ability to both guide and accept guidance from team members
• Professional attitude and conduct appropriate for a regulated industry

This role is based out of Carlsbad and can be flexible/hybrid with regular onsite (not remote). The expected salary range for this position based on the primary location of Carlsbad, CA is $100,000-125,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Relocation benefits are not offered for this role. Benefits

Who we are
GenMark is now a proud member of the Roche Group, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. As a global leader in healthcare, Roche Diagnostics offers a broad portfolio of products, tools and services that help in the prevention, diagnosis and management of diseases like HPV, HIV, hepatitis and diabetes as well as other medical conditions, such as fertility and blood coagulation. With the addition of GenMark to the Roche Group, syndromic infectious disease diagnostics is now added to the long list of disease states and conditions that the Roche Group addresses. GenMarks ePlex true sample-to-answer system offers unique solutions to address the most significant challenges facing clinical laboratories, while supporting hospital systems to deliver patient-centered, value-based care. ePlex streamlines the diagnostic workflow from physician order entry to the final test report and is the true sample-to-answer solution designed to improve patient care, reduce costs, and increase lab efficiency. GenMark is headquartered in Carlsbad, California.

GenMark is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individuals race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law
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