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Related Questions
Who can benefit from using PRB.org?
PRB.org can be useful for anyone interested in population-related issues, including policymakers, researchers, educators, students, journalists, and advocates. Their resources are accessible to the general public, and they offer tailored training and technical assistance to professionals in the field.
How can I access PRB.org's data and analysis?
PRB.org's resources are freely available on their website, including interactive data tools, reports, and briefs. They also offer customized data and analysis services for clients who require more specific or in-depth information.
Is PRB.org trustworthy?
Yes, PRB.org is a trusted source for information on population, health, and environment issues. They use rigorous research methods and collaborate with leading experts in the field to ensure the accuracy and reliability of their data and analysis.
Does PRB.org have any partnerships?
Yes, PRB.org partners with a range of organizations, including UN agencies, governments, universities, and non-profit organizations, to promote sustainable policies and improve health outcomes.
What is PRB.org's ultimate goal?
PRB.org's ultimate goal is to promote sustainable development and improve individual and collective well-being by providing evidence-based research and advocacy on population-related issues. They strive to empower individuals and communities to make informed decisions that ultimately lead to a better future for all.
What is PRB.org?
PRB.org is a non-profit organization that provides up-to-date data and analysis on population, health, and environment issues around the world. They are dedicated to promoting sustainable policies and improved health outcomes through evidence-based research and advocacy.
What type of information can I find on PRB.org?
PRB.org provides a wealth of information on various population-related topics, such as fertility, mortality, migration, aging, family planning, and reproductive health. You can also find data and analysis on environmental issues, such as climate change, sustainable development, and conservation.
How does PRB.org make an impact?
PRB.org works to promote evidence-based policies and programs that improve health outcomes and sustainable development. They collaborate with local and global partners to provide technical assistance, training, and advocacy on key population-related issues.
How does PRB.org stay up-to-date?
PRB.org has a team of experts who monitor and analyze global population trends and health and environment issues. They collaborate with leading researchers and organizations to ensure their data and analysis are accurate and reflect the latest research and development.
Can I contribute to PRB.org?
Yes, PRB.org accepts donations and offers opportunities for individuals and organizations to support their work. You can also share their resources and engage with them on social media to help spread the word about their mission and impact.
Popular Questions
What is pRB in cancer?
The RB1 gene provides instructions for making a protein called pRB. This protein acts as a tumor suppressor, which means that it regulates cell growth and keeps cells from dividing too fast or in an uncontrolled way.
What is p53 and pRB?
pRb and p53 are the two major tumor suppressors. Their inactivation is frequent when cancers develop and their reactivation is rationale of most cancer therapeutics. When pRb and p53 are genetically inactivated, cells irreparably lose the antitumor mechanisms afforded by them.
Why does inactivation of pRB lead to cancer?
Several studies have demonstrated that inactivation of pRB not only allows inappropriate proliferation, but also undermines mitotic fidelity, leading to genome instability and ploidy changes. Such properties promote tumor evolution and correlate with increased resistance to therapeutics and tumor relapse.
What is pRB and why may it be important in cancer development?
The retinoblastoma tumor suppressor protein (pRB) is a known regulator of cell-cycle control; however, recent studies identified critical functions for pRB in regulating cancer-associated gene networks that influence the DNA damage response, apoptosis, and cell metabolism.
What is the pRb gene responsible for?
The RB1 gene provides instructions for making a protein called pRB. This protein acts as a tumor suppressor, which means that it regulates cell growth and keeps cells from dividing too fast or in an uncontrolled way.
What is pRb cancer?
Introduction. The retinoblastoma protein (pRB) was the first protein identified as a tumor suppressor. pRB function is lost in 98% of the rare childhood malignancy retinoblastoma, in which the RB1 gene was traced to a locus on chromosome 13 and subsequently sequenced (1–4).
What is p53 and pRb?
pRb and p53 are the two major tumor suppressors. Their inactivation is frequent when cancers develop and their reactivation is rationale of most cancer therapeutics. When pRb and p53 are genetically inactivated, cells irreparably lose the antitumor mechanisms afforded by them.
Why does inactivation of pRb lead to cancer?
Several studies have demonstrated that inactivation of pRB not only allows inappropriate proliferation, but also undermines mitotic fidelity, leading to genome instability and ploidy changes. Such properties promote tumor evolution and correlate with increased resistance to therapeutics and tumor relapse.
What is pRb in cell cycle?
pRB is one member of a family of structurally and functionally conserved proteins that play a key role in negative regulation of the cell cycle via binding to E2F transcription factors. Despite such similarity, pRB is the only member required for DNA damage-induced arrest.
What is the role of pRb in the G1 S transition?
The key regulator of the G1/S transition is the retinoblastoma gene product (pRB). It prevents the transcription of genes required for S-phase progression by repressing E2F transcription factors. An increase in Cdk phosphorylation of pRB causes the release of E2F transcription factors and advancement into S phase.
How does pRb control cell cycle progression?
The Rb protein is a tumor suppressor, which plays a pivotal role in the negative control of the cell cycle and in tumor progression. It has been shown that Rb protein (pRb) is responsible for a major G1 checkpoint, blocking S-phase entry and cell growth.
What does the pRb protein do?
The RB1 gene provides instructions for making a protein called pRB. This protein acts as a tumor suppressor, which means that it regulates cell growth and keeps cells from dividing too fast or in an uncontrolled way.
Is PRB a good journal?
The most highly cited journal in condensed matter physics, PRB provides outstanding depth and breadth of coverage, combined with unrivaled context and background for ongoing research by scientists worldwide.
Is PRB a Q1 journal?
Physical Review B is a journal covering the technologies/fields/categories related to Condensed Matter Physics (Q1); Electronic, Optical and Magnetic Materials (Q1).
How do you cite a PRB article?
APA citation style: Population Reference Bureau. (2001) Population Reference Bureau PRB . United States. [Web Archive] Retrieved from the Library of Congress, https://www.loc.gov/item/lcwaN0009040/.
What is PRB network?
A E-UTRA PRB (Physical Resource Block) is defined as consisting of 12 consecutive subcarriers for one slot (0.5 ms). A PRB is the smallest element of resource allocation assigned by the eNB scheduler. If you enjoy using our glossary, here are some other useful resources you might like...
How is PRB utilization calculated in LTE?
The answer is at the end of this article. Physical Resource Block (PRB) = 2*Resource Block = 12 Subcarriers x 14 OFDM in 1ms.
What is RB and PRB?
The Rb protein is a tumor suppressor, which plays a pivotal role in the negative control of the cell cycle and in tumor progression. It has been shown that Rb protein (pRb) is responsible for a major G1 checkpoint, blocking S-phase entry and cell growth.
What is high PRB?
High PRB Utilization && Low User Number => that means serving UEs enjoying almost very satisfied throughput regarding to LTE 4G Signal they can see in their handsets.
What is a good impact factor?
In most fields, the impact factor of 10 or greater is considered an excellent score while 3 is flagged as good and the average score is less than 1.
How do I submit to PRB?
Submissions formatted in REVTeX or MS WORD are preferred. Upload the main body of the manuscript (including figures, tables, captions, etc.) to the Submissions server as a single file. Also send a cover letter, auxiliary files and figures, and Supplemental Material via the Submissions server.
Is Physical Review Letters a good journal?
As also confirmed by various measurement standards, which include the Journal Citation Reports impact factor and the journal h-index proposed by Google Scholar, many physicists and other scientists consider Physical Review Letters to be one of the most prestigious journals in the field of physics.
What is PRB in statistics?
The Population Reference Bureau (PRB) is a private, nonprofit organization specializing in collecting and supplying statistics necessary for research and/or academic purposes focused on the environment, and health and structure of populations.
What does PRB website mean?
Pharmaceutical Resources Branch (PRB) | Developmental Therapeutics Program (DTP)
How do you cite PRB?
Chicago citation style: Population Reference Bureau. Population Reference Bureau PRB . United States, 2001. ... APA citation style: Population Reference Bureau. (2001) Population Reference Bureau PRB . United States. ... MLA citation style: Population Reference Bureau. Population Reference Bureau PRB .
What is the World Population data Sheet?
The 2022 World Population Data Sheet, published annually by the Population Research Bureau (PRB), provides the latest data on key population, health, and environment indicators for major world regions and over 200 countries and territories.