Neuroectodermal tumor pathology outlines
Immunohistochemical studies show that the tumor cells are positive for CD99 (diffuse, membranous) and NKX2.2, while they are negative for cytokeratin cocktail, S100 protein, SMA, desmin and CD45. RT-PCR demonstrates the presence of an EWSR1-FLI1 fusion,...
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A rare benign tumor of neuroectodermal origin with biphasic population of neuroblastic cells and pigmented epithelial cells Terminology First described by Krompecher in …
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Identify the etiology of primitive neuroectodermal tumor medical conditions and emergencies. Outline the evaluation of primitive neuroectodermal tumor. Review the management options available for primitive …
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Primitive neuroectodermal tumors (PNETs) represents a biologically aggressive, poorly differentiated malignant neoplasm that demonstrates cellular differentiation that …
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Ewing’s sarcoma/PNET are small round cell tumors showing a varying degree of neuroectodermal differentiation. They are one of the commonest tumors of childhood and occur in bone and …
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Primitive neuroectodermal tumor (PNET) is a kind of extremely rare and highly aggressive, small round cell tumor, with poor prognosis. It develops from the primitive nerve …
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Ewing’s sarcoma (ES)/primitive neuroectodermal tumor (PNET) is a small round cell tumor with simple sarcoma-specific genetic alterations resulting in TET/FET family member and ETS family member fusion proteins [1]. …
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A malignant gastrointestinal neuroectodermal tumor (GNET) is an ultra-rare primary neoplasm with a distinctive histopathological, immunohistochemical, molecular, and ultramicroscopic …
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In this paper, we will outline the pathological features of ESFT, review the current concepts about their sarcomagenesis, discuss their capacity for multipotential differentiation, and focus on the controversies and impact of …
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